Increased seminal plasma lead levels adversely affect the fertility potential of sperm in IVF

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Increased seminal plasma lead levels adversely affect the fertility potential of sperm in IVF.

BACKGROUND Lead remains in high levels in the environment and is known to reduce fertility in animal models, but a direct link between lead exposures and human infertility has not yet been established. METHODS In a prospective, double-blind study of the metal ion levels and sperm function, semen was obtained from partners of 140 consecutive women undergoing their first IVF cycle. Lead in semi...

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P-79: The Correlation between Nitric Oxide Levels in Seminal Plasma with Human Sperm Parameters

Background: Defective sperm quality is a significant cause of infertility in men. It is known that nitric oxide (NO) is a highly reactive free radical gas which has a dual function, being both a cytotoxic and necessary molecule for normal sperm production. Materials and Methods: To investigate correlation between NO levels with sperm parameters, a case-control study were designed with total of ...

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Lead level in seminal plasma may affect semen quality for men without occupational exposure to lead

BACKGROUND Infertility affects approximately 10-15% of reproductive-age couples. Poor semen quality contributes to about 25% of infertile cases. Resulting from the direct effect on testicular function or hormonal alterations, heavy metals exposure has been related to impaired semen quality. The objective of this study was to assess the level of lead in the seminal plasma in men without occupati...

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Biomarkers of in vivo fertility in sperm and seminal plasma of fertile stallions.

The global proteome of sperm and seminal plasma of fertile stallions was investigated to determine whether associations with relative in vivo fertility exist. Seven stallions at stud in a commercial breeding station were collected throughout the breeding season and bred to a total of 164 mares to determine conception rates. On three occasions during the breeding season, raw semen was obtained f...

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Determination of some seminal plasma indices, sperm density and sperm motility in the Persian sturgeon Acipenser persicus

Some biological aspects of semen were investigated in the Persian sturgeon, Acipenser persicus, by determination of seminal plasma indices (ionic composition and osmolality), sperm density and their relationships with sperm motility. The osmolality of seminal plasma ranged from 42.00 to 111.00 mOsmol Kg-1. The concentrations of Sodium (Na+), Potassium (K+), Chloride (Cl-), Calcium (Ca2+) and Ma...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2003

ISSN: 1460-2350

DOI: 10.1093/humrep/deg020